Simeox as a standard of care
At PhysioAssist, we are investing in basic and clinical research to establish Simeox as a standard of care in the airway clearance management of patients suffering from obstructive lung diseases. Clinical validation is essential to achieve this goal and well as to drive coverage in homecare markets.
Main Clinical Trials
Mucosim Trial
Impact of Simeox Airway Clearance Device on Respiratory Function and Symptoms in Adult Patients with Cystic Fibrosis.
Multicentric Randomized Controlled Trial.
Primary endpoint: Evolution of Total lung resistance (Airwave Oscillometry System).
Control group: autogenic drainage.
Number of patients : 42 adult patients with CF.
Homecare CF trial
Long Term Efficacy and Acceptability of Simeox Used Autonomously and at Home in Patients With Cystic Fibrosis.
Multicentric Randomized Controlled Trial.
Primary endpoints: Respiratory score domain CFQ-R and FEV1.
Control group: standard care with CPT.
Number of patients: 224 patients with CF > 14 years.
HOMECARE PEDIATRIC CF TRIAL
Efficacy of Simeox Airway Clearance Therapy in Children With Cystic Fibrosis.
Monocentric Randomized Controlled Trial.
Primary endpoint: Evolution of lung resistance (IOS).
Control group: standard care with CPT.
Number of patients: 40 pediatric patients with CF.
Proof of concept trial in CF
Effects of Simeox on Airway Clearance in Cystic Fibrosis.
Monocentric Cross-over Randomized Controlled Trial.
Primary endpoint: Weight of sputum secretion.
Control group: autogenic drainage.
Number of patients: 20 adult patients with CF.
Proof of concept trial in COPD
Effects of Simeox on Static Hyperinflation in Patients With COPD
Monocentric Cross-over Randomized Controlled Trial.
Primary Endpoint: Change in FRC after and 30 min.
Control group: PEP therapy.
Number of partients: 25 adult patients with COPD.
Clinical Documentation
CF DE. SCHMIDT & DR. FABRICIUS (ULM) Health science Report 2022
Voir la version interactive Télécharger le PDFCF / DR SCHMIDT & DR FABRICIUS / ERS 2021
Télécharger le PDFCF / PR SANDS / ERS 2021
Télécharger le PDFCOPD / SOLOVIK ET BODNAROVA / ERS 2020
Télécharger le PDFCF / PROFFIT, MAGNI, DESBOIS, MORIN / ERS 2020
Télécharger le PDFBENCH TEST / ERS 2020
Télécharger le PDFCOPD / Mihaltan et al. - ERS 2018 / ATS 2019
Télécharger le PDFCOPD / Mihaltan et al. - CPLF 2019
Télécharger le PDFCF / Sands et al. - ECFS 2019
Télécharger le PDFNon CF-BE / Kolek et al, ERS 2019
Télécharger le PDFNon CF-BE / Sliwinski et al. - ERS 2018 / ATS 2019
Télécharger le PDFClinical Notebook n°2
Télécharger le PDFClinical Notebook n°3
Télécharger le PDFClinical Notebook n°4
Télécharger le PDFClinical Notebook n°5
Télécharger le PDFThe expected results
- Mucus that interferes with your breathing is easily mobilised.
- No more waking up at night because of coughing
- You are once again serene when you go out shopping, visit your friends or your family.
- You don’t have to exhaust yourself to get your sputum out.
- You preserve your energy to live the rest of your day to the fullest.
Symposiums / Communications
ERS2022 - Workshop
"A new era in distal mucus management"
EU Virtual Roundtable 1 (Simeox therapy in CF)
Reinforcement of IV therapy - May 2021
EU Virtual Roundtable 2 (Simeox therapy in CF)
Mobilization of mucus during regular care - May 2021
EU Virtual Roundtable 3 (Simeox therapy in CF)
Personalized medicine / Home rehabilitation - May 2021
ERS 2018 Industry Practical Workshop
Key Moments
ERS 2018 Industry Practical Workshop
Full Version
Scientific Session
Pulmonology Congress, Warsaw 2018 - Simeox Technology
Scientific Session
Pulmonology Congress, Warsaw 2018 - Simeox Discussion
Scientific Session
Pulmonology Congress, Warsaw 2018 - Dr Pérez and Mr Gauchez
Scientific Session
Pulmonology Congress, Warsaw 2018 - Prof. Solovic and Mrs Bodnarova
Scientific Session
Pulmonology Congress, Warsaw 2018 - Prof. Mihaltan and Dr Cosei
Scientific Session
Pulmonology Congress, Warsaw 2018 - Dr Elena Amelina
Scientific Session
Pulmonology Congress, Warsaw 2018 - Prof. Paweł Śliwiński
Scientific Session
Pulmonology Congress, Warsaw 2018 - Prof. Vítězslav Kolek
Committee Advisors
Martine Reynaud‑Gaubert
Professor of Medicine and Head of Department Pneumology, rare respiratory disease, cystic fibrosis
Martine Reynaud-Gaubert
Professor of Medicine and Head of Department Pneumology, rare respiratory disease, cystic fibrosis
Hospital Practitioner Hospital north of Marseille - APHM
Medical Officer of Lung Transplant Program Adults
Marseille Coordinator of the Competence Center for Pulmonary Hypertension weans
Coordinator of Resource Center and Competence Cystic Fibrosis (CRCM) Coordinator of Disease Competence Center Rare Lung adult
Professor Reynaud-Gaubert directs clinical studies and PhysioAssist publications since 2011 to produce and develop scientific knowledge of PhysioAssist the benefit of patients.
Hughes Gauchez
Osteopathy physiotherapist specializing in respiratory - CKRF Lille
Hughes Gauchez
Osteopathy physiotherapist specializing in respiratory - CKRF Lille
Referent Physiotherapist for the association “Vaincre la mucoviscidose”
Founding president of the AMK Representative IPGCF for France (International Physiotherapy Group for Cystic Fibrosis)
President of P2R Training - Autogenous drainage and respiratory physiotherapy techniques
Hugues Gauchez accompanies Physio-Assist in defining the Simeox use patterns by physiotherapists. He is an expert autogenous drainage and adopts Simeox into daily practice, in assisted sessions or during patient autonomy implementation.
Sophie Jacques
Respiratory Physiotherapist - Rennes
Sophie Jacques
Respiratory Physiotherapist - Rennes
Autogenous drainage trainer in France, Belgium and Eastern countries
President of the French Association “Mucoviscidose et Kinésithérapie” (AMK)
Respiratory Rehabilitation Inter-Universities Diploma
Sophie Jacques uses Simeox with her patients in her daily practice and helps them to autonomously manage their drainage. Sophie helps Physioassist with the Simeox training, she brings and shares her Simeox expertise with new physiotherapist users.
Mathilde Proffit
Respiratory Physiotherapist, La Bulle, NICE
Mathilde Proffit
Junior trainer in autogenic drainage in France and Eastern Europe, lecturer in respiratory specialties at the Physiotherapy Schools of Nice and Saint Michel - Paris.
University graduations speciality paediatrics Paris Descartes / Stetho-acoustic training / pulmonary ultrasound / paediatric manual therapy / medical hypnosis / yoga teacher
Mathilde worked at the Cystic Fibrosis Center of the Necker Enfants Malades University Hospital, Paris - where she started using Simeox on various patients, both paediatric and adult, some with very severe pulmonary conditions. She now practices in Nice in her respiratory rehabilitation practice - La Bulle, and uses Simeox with all her patients.
She has a great deal of experience with Simeox, having used it for over 3 years, with consistently excellent clinical results.
Testimonials
COPD
Colette, France
Bronchiectasis
Fabienne, France
COPD
Nadine, France
Cystic fibrosis
Sarah, Germany
Cystic fibrosis
Perrine, France
COPD
Marie-Claude, France
COPD
Yves, France
Cystic fibrosis
Antoine, France
Dyspnea - COPD
Cystic fibrosis
Alice, France
Bronchial drainage - COPD
Simeox Testimony
Lysianne, France
Simeox Testimony
Gil, France
Simeox Testimony
Michèle, France
Simeox Testimony
Ghislaine, France